Weight loss drugs have develop into a hot topic as public health authorities and pharmaceutical firms seek solutions to the growing global obesity epidemic.
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Some oral drug made by Pfizer produces similar weight loss and works faster than the rival Latest Nordiskblockbuster injection of Ozempic, according to a peer-reviewed Phase 2 clinical trial published on Monday.
The results were presented at a medical conference late last yr and didn’t compare Pfizer with Ozempic or other weight loss drugs. JAMA network is only now publishing a peer-reviewed study.
The Pfizer study involved 411 adults with type 2 diabetes who either took the brand-name pill or dunuglipronetwice a day or a placebo.
The study found that patients who took the 120-milligram version of Danuglipron lost a median of about 10 kilos, or 4.60 kilograms, over 16 weeks.
AND Phase III clinical trial on Ozempic found that adults who took the 1-milligram version of the injection lost a median of about 9.9 kilos, or 4.53 kilograms, over a median of 30 weeks. Patients take this injection once per week.
The results suggest that Danuglipron could also be as effective in weight loss as Ozempic.
Pfizer’s drug can also offer a bonus as an oral treatment option relatively than frequent injections.
Each Danuglipron and Ozempic belong to a category of medicine called glucagon-like peptide-1 agonists.
They mimic a hormone produced within the gut called GLP-1, which signals to the brain when an individual is full.
Medications can even help people treat type 2 diabetes because they stimulate the discharge of insulin from the pancreas, lowering blood sugar levels.
Latest York-based Pfizer is the most recent pharmaceutical company to enter the hit weight loss drug market.
Novo Nordisk’s Ozempic and Wegovy have been within the national highlight in recent times as “miracles” for weight loss.
Hollywood celebrities, social media influencers and billionaire tech mogul Elon Musk reportedly used popular injections to do away with unwanted kilos.
But experts to talk drugs can further perpetuate a dangerous food plan culture that idealizes weight loss and thinness.
Some patients who stop taking their medications also complain of uncontrollable weight gain.
Greater than 2 in 5 adults are obese, according to National Institute of Health. About 1 in 11 adults are severely obese.